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| Name and address | License | Places |
|---|---|---|
| South Coast Chinese Cultural Association 9 Truman ST | School-age center | 43 |
| South Coast Chinese Cultural Association 9 Truman ST | Preschool center | 84 |
| Spectrum Montessori at Portola Springs 950 Tomato Springs | Preschool center | 192 |
| Spectrum Montessori at Woodbury 5725 Trabuco Road | Preschool center | 120 |
| Spectrum Montessori at Woodbury 5725 Trabuco Road | Infant center | 60 |
| St. Andrew's Children's Center 4400 Barranca PKWY | Infant center | 64 |
| The Children's Center at Taco Bell One Glen Bell Way | Preschool center | 44 |
| The Children's Center at Taco Bell One Glen Bell Way | Infant center | 16 |
| The Dolphin Club Day Care Center 155 Eastshore | School-age center | 135 |
| Turtle Rock Preschool 1 Concordia West | Preschool center | 136 |
| Turtle Rock Preschool 1 Concordia West | Infant center | 20 |
| TUSD Kindergarden Readiness-Myford 3181 Trevino Drive | Preschool center | 24 |
| Tutor Time Child Care/Learning Center 12860 Central Park Avenue | Preschool center | 172 |
| Tutor Time Child Care/Learning Center 12860 Central Park Avenue | Infant center | 32 |
| Tutor Time Child Care/Learning Center 12860 Central Park Avenue | School-age center | 28 |
| U.C. Irvine-Children's Center 6533 Adobe CIR | Preschool center | 54 |
| U.C. Irvine-Early Childhood Education Center 501 Adobe CIR | Preschool center | 118 |
| U.C. Irvine-Extended Day Care Center 6537 Adobe CIR | School-age center | 45 |
| U.C. Irvine-Infant Toddler 533 California | Infant center | 72 |
| University Montessori School of Irvine 101 Russell PL | Preschool center | 156 |
| University Montessori School of Irvine - Infant 101 Russell PL | Infant center | 40 |
| University Synagogue Preschool 3400 Michelson Drive | Preschool center | 90 |
| Village Montessori School of Irvine 4552 Sandburg Way | Preschool center | 65 |
| Westpark Montessori School of Irvine, Inc. 11 San Leandro | Infant center | 32 |
| Westpark Montessori School of Irvine, Inc. 11 San Leandro | Preschool center | 135 |
| Woodbridge Children's School 4925 Alton Pkwy | Preschool center | 70 |